Translational Research

Rodent models and humans with disease/injury

  • Novel therapies including gene therapy, stem cell therapy, neural stimulation, and intermittent hypoxia to treat neuro-muscular disorders that compromise breathing:
    Gene Therapy (AAV)

    Gene Therapy (AAV)

    • Spinal Cord Injury (SCI)
    • Amyotrophic Lateral Sceloris (ALS)
    • Muscular Dystophy (MD)
    • Pompe Disease
    • Parkinson’s Disease (PD)
    • Sepsis
    • Sleep Apnea
    • Multiple Sclerosis (MS)
    • Spinal Muscular Atrophy
  • Fundamental principles derived from studies of respiratory function have already proven relevant in other motor systems, including walking, arm movements and speech/swallowing. Thus, a secondary theme of the Center for Respiratory Research and Rehabilitation is the translation to non-respiratory motor systems.

Neuromuscular Stimulation

Inspiratory/Expiratory Threshold Loading

Inspiratory/Expiratory Threshold Loading

Therapeutic Intermittent Hypoxia

Therapeutic Intermittent Hypoxia